Japan market size · Drug class

SGLT2 inhibitors in Japan

SGLT2阻害薬

The prescription value of SGLT2 inhibitors (6 molecules) in Japan was an estimated ¥235 billion in FY2024. Value changed +15.1% year on year and +21.7% a year on average over the last three years. The largest molecule is Dapagliflozin (41%). In addition, 3 combination products totalled ¥63.4 billion.

¥235bnValue FY2024 (single agents)

+15.1%Year on year

+21.7%3-year average growth

Trend and molecules

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Trend (single agents)

Prescription value (est.)YoY upYoY down

By molecule (FY2021 = 100)

Molecules in this class

Dapagliflozinダパグリフロジン EmpagliflozinエンパグリフロジンIpragliflozin L-Prolineイプラグリフロジン　Ｌ－プロリンCanagliflozin Hydrateカナグリフロジン水和物Tofogliflozin Hydrateトホグリフロジン水和物Luseogliflozin Hydrateルセオグリフロジン水和物Empagliflozin / Linagliptinエンパグリフロジン・リナグリプチンTeneligliptin Hydrobromide Hydrate / Canagliflozin Hydrateテネリグリプチン臭化水素酸塩水和物・カナグリフロジン水和物Sitagliptin Phosphate Hydrate / Ipragliflozin L-Prolineシタグリプチンリン酸塩水和物・イプラグリフロジン　Ｌ－プロリン

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About the data

Values are estimates: prescription volumes from Japan's NDB Open Data (Ministry of Health, Labour and Welfare; excluding public-expense claims), FY2015–FY2024, multiplied by the NHI reimbursement price of each product at the time of each release (nominal). All strengths and brands of the molecule are combined. Japanese fiscal years run from April to March (FY2024 = April 2024 – March 2025). Until FY2023 the NDB lists only the top products by volume in each therapeutic class; years in which a molecule is not listed are shown as “not listed”. Growth rates compare the same products in consecutive years and are chained; the 3-year rate is not shown when the base year value is below one tenth of the latest year. The comparison with related drugs is an index with FY2021 = 100. Supply: MHLW, as of 2026-09-27.