Japan market size · Drug class

Bisphosphonates in Japan

ビスホスホネート

The prescription value of Bisphosphonates (6 molecules) in Japan was an estimated ¥36.1 billion in FY2024. Value changed -17.1% year on year and -8.5% a year on average over the last three years. The largest molecule is Ibandronate (35%).

¥36.1bnValue FY2024 (single agents)

-17.1%Year on year

-8.5%3-year average growth

Trend and molecules

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Trend (single agents)

Prescription value (est.)YoY upYoY down

By molecule (FY2021 = 100)

Molecules in this class

Ibandronate Sodium Hydrateイバンドロン酸ナトリウム水和物Alendronate Sodium Hydrateアレンドロン酸ナトリウム水和物Minodronic Acid Hydrateミノドロン酸水和物Sodium Risedronate Hydrateリセドロン酸ナトリウム水和物Zoledronic Acid Hydrateゾレドロン酸水和物Etidronate Disodiumエチドロン酸二ナトリウム

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About the data

Values are estimates: prescription volumes from Japan's NDB Open Data (Ministry of Health, Labour and Welfare; excluding public-expense claims), FY2015–FY2024, multiplied by the NHI reimbursement price of each product at the time of each release (nominal). All strengths and brands of the molecule are combined. Japanese fiscal years run from April to March (FY2024 = April 2024 – March 2025). Until FY2023 the NDB lists only the top products by volume in each therapeutic class; years in which a molecule is not listed are shown as “not listed”. Growth rates compare the same products in consecutive years and are chained; the 3-year rate is not shown when the base year value is below one tenth of the latest year. The comparison with related drugs is an index with FY2021 = 100. Supply: MHLW, as of 2026-09-27.